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Europe
GENTAUR
 +32
1658 9045
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1650 9045
info@gentaur.com
Av. de l' Armée 68
B-1040 Brussels
BELGIUM
France
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75005 Paris
Italy
tel 02 36 00 65 93
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Germany
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1658 9045
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1650 9045
Japan
tel +81 78 386 0860
fax +81 78 306 0296
Minaatojimaminami-manchi
Chuo-ku, Kobe
065-0047
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Deconjugating Enzymes, Inhibitors &
Substrates
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The
enzymes that
catalyze the removal
of ubiquitin from native conjugates, ubiquitin C-terminal extension
peptides, ubiquitin precursor proteins, linear poly-ubiquitin
fusions or disassembly of ubiquitin chains are known as
deconjugating enzymes (or deubiquitinating enzymes, DUBs). There
are also enzymes that specifically hydrolyze C-terminal isopeptide
bonds for ubiquitin-like proteins: SUMO-specific proteases (SENPs),
NEDD8-specific proteases (NEDP1,
COP9 signalosome) and ISG15-specific proteases (UBP43).
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Ubiquitin-Specific Proteins, human recombinant |
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Deconjugating Enzymes |
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Ataxin-3 (MJD protein 1) |
USP2CD (UBP41 catalytic domain) |
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Cat.#: E-341 (HIS-tagged) |
Cat.#: E-506 (HIS-tagged) |
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A20CD (TNFAIP3 catalytic domain) |
USP7CD (HAUSP catalytic domain) |
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Cat.#: E-344 (HIS-tagged) |
Cat.#: E-518 (HIS-tagged) |
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Bap1 |
USP14 |
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Cat.#: E-345 (HIS-tagged) |
Cat.#: E-544 |
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DUB3 |
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Cat.#: E-348 (HIS-tagged) |
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Inhibitors |
Substrate |
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Ubiquitin Aldehyde |
Ubiquitin AMC |
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Cat.#: U-201 |
Cat.#: U-550 |
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Ubiquitin Vinyl Sulfone |
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Cat.#: U-202 |
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ISG15-Specific Proteins, human recombinant |
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Deconjugating Enzyme |
Substrate |
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UBP43 (USP18) |
ISG15 AMC |
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Cat.#: E-600 (HIS-tagged) |
Cat.#: UL-553 |
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Inhibitors |
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ISG15 Aldehyde |
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Cat.#: UL-602 |
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ISG15 Vinyl Sulfone |
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Cat.#: UL-603 |
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