IL-2
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human IL2 liquid 3,10*6U 195 € rH IL-2 Recombinant Human Interleukin 2 Batch No.: IL2..... Specifications and Use Description Recombinant human IL-2 produced in Yeast is a single,non-glycosylated, polypeptide chain containing 133 amino acids, one pair of disulfide bond and with 125 cys. aa. mutated to Ala aa, having a molecular mass of approximately 15.4kD. Source YeastMolecular Mass Approximately 15.4kD.Purity ≥97%, as determined by SDS-PAGE and HPLC method.Endotoxin Level ≤1EU/ml, determined by the LAL method.Biological Activity Measured in a cell proliferation assay using an IL-2 dependentmurine cytotoxic T cell line, CTLL-2. The result of potency is 3.24×10 6IU/vial.Formulation Active ingredient : Recombinant human Interleukin 2 (rHuIL-2)Inactive ingredients: Sodium Acetate, Acetate Acid, Mannitol and Polysorbate-80. Storage Store at 2-8℃ for 2 years.Expiry Date 2008/07/10 for Batch No. of IL2DP-06-01.Human Interleukin 2 Human IL-2 (also known as TCGF) is an about 15.4KD factor produced mainly by activated CD4+ T cells. IL-2 induces cell cycle progression of resting cells in an antigen non-specific manner and allows clonal expansion of activated T cells. IL-2 also acts on activated B cells, monocytes, NK, LAK cells, and on oligodendroglial cells in vitro. In addition, IL-2 plays a role in hematopoiesis, tumor surveillance and anti-inflammatory reactions and hence is a central regulator of the immune response. Non-glycosylated IL-2 is biologically active. Recombinant human IL-2 is biologically active and can promote proliferation of T lymphocytes in culture.
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